ASMF Pro Learning Management System

This Project is to design and develop an online learning management system for students, which will be an open source learning management tools like blackboard, which will provide an online platform for conducting and taking classes online. Where students can register for the classes and get access to the online lectures provided by the instructor that can be in any file format. This system consists of a registration module where a new student can register and login. The students who got registered will get the access to register for the course. And instructor module has the separate registration and can have access to the student details and list of students registered for the course. The student module has student registration and login, at the registration page student need to provide with all the details like his name, email, phone number and it provide a student to add or drop a course and get access to the course description and details. The students can access the lectures in the portal provided by the instructor, the lecture can be in any type for example it can be a material or video or link to the source etc. The files can be of any format like pdf, doc, ppt, video etc. There will be an assignment submission portal or link where all the students can submit the assignment and can access their grades. The instructor module will have the different registration form and after login to their portal an instructor can have access to all the student details and list of students that has registered for the class and adding and removing a student. Instructor can send a notification email to all the students and can also notify through text messages via mobile phone. Instructor can provide the lecture through uploading and updating the materials and video lectures to the system so that all the students can access to the materials provided by the instructor. And the instructor can provide record on-screen activity to students for assist with software installation and course related support, with the help of screencast tools. Instructor has the portal to post the assignments and check the assignments posted by students and grade them

GSU Event Portal

This sophisticated web application, GSU Event Portal, would allow visitors to search for events happening around the city with the ability of paying for interested up-coming event using a debit/credit card. As the name implies, this web application would display tangible information of such event to event goers. The technology behind this application is to make visitors more informative and feature in dynamic events which might be live music, live festivals and many more. On the user interface, visitors should be able to search for up-coming events by city, time and event type. The result of the search would provide all events that will be happening at the specified time based on a visitor’s search criteria. Event organizers would as well be able to advertise their events ahead of time. The web application will be available on any device that could browse with internet connected and will be designed in three consoles: The Organizer console, Admin console and user interface. Organizer console will be able to create and edit events, view registration for an event and verify payments. The Admin console will be able to give permissions to Organizers and visitors, edit user’s profile and delete user account. The User interface console will be available to visitors and users who would like to register for an up-coming event. In addition to that, it will include map functionality that will show the event location on map. Visitors can only view event listings but to participate in an event, registration would be required for allocation of space

Antibacterial activity of ginger extracts and its essential oil on some of pathogenic bacteria

The antimicrobial activity of ginger extracts ( cold-water, hot-water, ethanolic and essential oil ) against some of pathogenic bacteria ( Escherichia coli , Salmonella sp , Klebsiella sp , Serratia marcescens, Vibrio cholerae , Staphylococcus aureus , Streptococcus sp) was investigated using Disc diffusion method , and the results were compared with the antimicrobial activity of 12 antibiotics on the same bacteria . The results showed that the ginger extracts were more effective on gram-positive bacteria than gram-negative . V. cholerae and S. marcescens,were the most resistant bacteria to the extracts used , while highest inhibition was noticed against Streptococcus sp (28 mm) . The ethanolic extract showed the broadest antibacterial activity ( 11 to 28 mm ) , in comparison with moderate activity of essential oil , it was observed that the cold-water extract was more effective on the bacteria than hot-water extract . Ginger ethanolic extract presented higher diameter of inhibition zone for Streptococcus sp than in Ciprofloxacin , Cefotaxime , Cefalotin , Cephalexin and Cephaloridine , also it was found a similarity between the higher inhibition zones of ethanolic extract of ginger and some antibiotics for S. aureus , E. coli , Salmonella sp and Klebsiella sp . V. cholerae and S. marcescens,also highly resistant to antibiotics . Phytochemical analysis of ethanolic extract of ginger revealed the present of glycosides, terpenoids, flavonids and phenolic compound

Evaluation of Retinol Level Among Preschool Children, Pregnant and Lactating Women Attending Primary Health Care Centres in Baghdad

Background: Vitamin A deficiency (VAD) is a major public health nutrition problem in the developing world. There have been no studies on this topic in Iraq. This study was designed to evaluate the serum retinol levels of preschool children, pregnant and lactating women. Objectives: The present study is an attempt to estimate the prevalence of vitamin A deficiency among preschool children, pregnant and lactating women attending primary health care centers in Baghdad, in addition to figure out the relation between vitamin A deficiency with some demographical, clinical, variables. Subjects and Methods: The study was conducted during the period from October to December 2009. The sample was comprised of 490 subjects, Lactating women pregnant women and under 6 year's old children attending ten primary health care centers in Baghdad. The data were collected through direct interview; blood samples were taken and analyze for serum retinol (SR) by HPLC analysis and hemoglobin (Hb) level, anthropometric measurement were obtained for the study sample. Results: The study showed that the prevalence of vitamin A deficiency in preschool aged children (below 6 years) was (38.3 %); and that for lactating women and pregnant women were (7.1 %) and (25 %) respectively. Forty percent of pregnant women, (25.8 %) of lactating women and a total of (58.6 %) preschool children were anemic, A correlation coefficient between SR and Hb concentrations was significant (N=490, r=0.533, P<0.0001). Conclusion: Vitamin A deficiency is a public health problem, this study shows that subjects in the 3 groups (preschool children, pregnant and lactating women) are at risk of VAD and anemia; nearly half of them had the co-occurrence of VAD and anemia. A close association between vitamin A deficiency and anemia with a correlation coefficient between SR and Hb concentrations was significant

Multi-objective NSGA-II based community detection using dynamical evolution social network

Community detection is becoming a highly demanded topic in social networking-based applications. It involves finding the maximum intraconnected and minimum inter-connected sub-graphs in given social networks. Many approaches have been developed for community’s detection and less of them have focused on the dynamical aspect of the social network. The decision of the community has to consider the pattern of changes in the social network and to be smooth enough. This is to enable smooth operation for other community detection dependent application. Unlike dynamical community detection Algorithms, this article presents a non-dominated aware searching Algorithm designated as non-dominated sorting based community detection with dynamical awareness (NDS-CD-DA). The Algorithm uses a non-dominated sorting genetic algorithm NSGA-II with two objectives: modularity and normalized mutual information (NMI). Experimental results on synthetic networks and real-world social network datasets have been compared with classical genetic with a single objective and has been shown to provide superiority in terms of the domination as well as the convergence. NDS-CD-DA has accomplished a domination percentage of 100% over dynamic evolutionary community searching DECS for almost all iterations

Enhancement in 3D dosimetry measurement using polymer gel and MRI

The effects of varying the concentrations of cross-linker N, N'-methyelene-bis-acrylamide (BIS) from 2% to 4%, and 2-hydroxyethylacrylate (HEA) monomer from 2% to 4% at 5% gelatin on the dose response of BIS–HEA–gelatin (BHEAG) aqueous polymer gel dosimeters have been studied using magnetic resonance imaging (MRI) for relaxation rate (R2)R2) of water proton. The dosimeters were irradiated with 60Co teletherapy γγ-ray source at a constant dose rate, receiving doses up to 30 Gy. The radiation polymerization occurs and increases with increasing initial dose. R2R2 is found to decrease mono-exponentially with depth inside the polymer gel and depend strongly upon the initial concentrations of co-monomers (HEA and BIS). Dose–depth map for BHEAG gel was determined for different concentrations of co-monomer (HEA and BIS). The percentage dose depth was also evaluated which leads to a good agreement with the ionization chamber measurements

A proposed model of xeno-keratoplasty using 3D printing and decellularization

Corneal opacity is a leading cause of vision impairment and suffering worldwide. Transplantation can effectively restore vision and reduce chronic discomfort. However, there is a considerable shortage of viable corneal graft tissues. Tissue engineering may address this issue by advancing xeno-keratoplasty as a viable alternative to conventional keratoplasty. In particular, livestock decellularization strategies offer the potential to generate bioartificial ocular prosthetics in sufficient supply to match existing and projected needs. To this end, we have examined the best practices and characterizations that have supported the current state-of-the-art driving preclinical and clinical applications. Identifying the challenges that delimit activities to supplement the donor corneal pool derived from acellular scaffolds allowed us to hypothesize a model for keratoprosthesis applications derived from livestock combining 3D printing and decellularization

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Methods: We did an international, multicentre, randomised, placebo-controlled trial in 164 hospitals in 15 countries. Patients were enrolled if the responsible clinician was uncertain whether to use tranexamic acid, were aged above the minimum age considered an adult in their country (either aged 16 years and older or aged 18 years and older), and had significant (defined as at risk of bleeding to death) upper or lower gastrointestinal bleeding. Patients were randomly assigned by selection of a numbered treatment pack from a box containing eight packs that were identical apart from the pack number. Patients received either a loading dose of 1 g tranexamic acid, which was added to 100 mL infusion bag of 0·9% sodium chloride and infused by slow intravenous injection over 10 min, followed by a maintenance dose of 3 g tranexamic acid added to 1 L of any isotonic intravenous solution and infused at 125 mg/h for 24 h, or placebo (sodium chloride 0·9%). Patients, caregivers, and those assessing outcomes were masked to allocation. The primary outcome was death due to bleeding within 5 days of randomisation; analysis excluded patients who received neither dose of the allocated treatment and those for whom outcome data on death were unavailable. This trial was registered with Current Controlled Trials, ISRCTN11225767, and ClinicalTrials.gov, NCT01658124. Findings: Between July 4, 2013, and June 21, 2019, we randomly allocated 12 009 patients to receive tranexamic acid (5994, 49·9%) or matching placebo (6015, 50·1%), of whom 11 952 (99·5%) received the first dose of the allocated treatment. Death due to bleeding within 5 days of randomisation occurred in 222 (4%) of 5956 patients in the tranexamic acid group and in 226 (4%) of 5981 patients in the placebo group (risk ratio [RR] 0·99, 95% CI 0·82–1·18). Arterial thromboembolic events (myocardial infarction or stroke) were similar in the tranexamic acid group and placebo group (42 [0·7%] of 5952 vs 46 [0·8%] of 5977; 0·92; 0·60 to 1·39). Venous thromboembolic events (deep vein thrombosis or pulmonary embolism) were higher in tranexamic acid group than in the placebo group (48 [0·8%] of 5952 vs 26 [0·4%] of 5977; RR 1·85; 95% CI 1·15 to 2·98). Interpretation: We found that tranexamic acid did not reduce death from gastrointestinal bleeding. On the basis of our results, tranexamic acid should not be used for the treatment of gastrointestinal bleeding outside the context of a randomised trial

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens